Endocrine Abstracts

A 16-years old boy was referred for endocrine assessment of growth retardation. He had normal growth to age 7 years (tallest in his class) following which he sustained frontal head injury and subsequently exhibited growth retardation. There was no other confounding history. At age 16, height=1.47 m (below 3rd centile; mid-parental height=1.77 m), BMI=21, he was pre-pubertal. Full blood count, biochemistry and chest X-ray were unremarkable. He was 3 years behind in bone age, ha...

An 87-year-old lady was admitted to hospital with severe unexplained hypoglycaemia with capillary glucose of 1.8 mmol/l and went on develop recurrent episodes of symptomatic hypoglycaemia during this admission. She had a background history of diabetes mellitus, well under controlled with diet and a previous diagnosis of solitary fibrous pleural tumour of left lung, which was resected completely in 2013 but reoccurred in 2022 with left sided pleural effusion. Her liver and rena...

Case History: A 20-year-old lady was referred by GP to the endocrine clinic with frequent and gradually worsening non-specific headaches and primary amenorrhoea. She denied cyclical pelvic pain, acne, hirsutism or anosmia. She consulted her GP for delay in menarche when she was 16 years old but was advised to wait until the age of 18 years but unfortunately it was the middle of the Covid-19 pandemic and hence the delay in the referral. There was past medical history of migrain...

Case History: We report a case of 81-year-old female of white background who was admitted after a fall with long lie and confusion. On arrival, she was found to be hypotensive BP-85/46 mmHg, Hypothermic-temp-20.9 and bradycardic HR-46 beats/min, GCS was 13/15 with low normal CBG-4.0 mmol/l. She has a history of chronic hyponatraemia, thyroidectomy 9 years prior to this presentation and a previous admission with fall leading to pelvic fractures. During that admission she was st...

Case History: A 64-year-old gentleman presented to the emergency department with acute onset dizziness, nausea, vomiting and difficulty in standing. Although his symptoms lasted only for a few hours, his neurological examination was unremarkable. His past medical history included atrial fibrillation, factor V Leiden deficiency and previous left lower limb DVT. He was not on any medications that can cause hyperprolactinaemia. The stroke team who reviewed him initially diagnosed...

Controversy exists as to the role of adrenal venous sampling in the assessment of primary aldosteronism (PA). There is no consensus as to how best to define successful outcome post resection of aldosterone producing adenoma (APA). We performed a retrospective analysis of the outcome of patients following unilateral adrenalectomy without pre-operative venous sampling. The study included 14 patients (9 males; mean age 47 yrs (r: 38–59 yrs) with PA and CT identified u...